influence of age and gender on the profile of exhaled volatile organic compounds analyzed by an electronic nose
年齡和性別對(duì)呼氣揮發(fā)性有機(jī)物圖譜的影響研究
silvano dragonieri1, vitaliano nicola quaranta1, pierluigi carratu1, teresa ranieri1, onofrio resta1
abstract
we aimed to investigate the effects of age and gender on the profile of exhaled volatile organic compounds. we evaluated 68 healthy adult never-smokers, comparing them by age and by gender. exhaled breath samples were analyzed by an electronic nose (e-nose), resulting in “breathprints”. principal component analysis and canonical discriminant analysis showed that older subjects (≥ 50 years of age) could not be distinguished from younger subjects on the basis of their breathprints, as well as that the breathprints of males could not distinguished from those of females (cross-validated accuracy, 60.3% and 57.4%, respectively).therefore, age and gender do not seem to affect the overall profile of exhaled volatile organic compounds measured by an e-nose.
評(píng)估了68名健康的成人從不吸煙者，并用年齡和性別。呼氣樣本通過(guò)電子鼻(e-nose)進(jìn)行分析。導(dǎo)致“呼吸印記”。主成分分析與典型判別分析表明，老年人(≥50歲)不能與年輕的受試者根據(jù)他們的呼吸印，以及男性無(wú)法與女性區(qū)分(交叉驗(yàn)證的準(zhǔn)確性，60.3%因此，年齡和性別似乎不會(huì)影響整體用電子鼻測(cè)量呼出的揮發(fā)性有機(jī)化合物的分布。
keywords: breath tests; volatile organic compounds; electronic nose.
關(guān)鍵詞：呼吸試驗(yàn)；揮發(fā)性有機(jī)化合物；電子鼻